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Prozac (fluoxetine hydrochloride) is a psychotropic drug for oral administration. It is also marketed for the treatment of premenstrual dysphoric disorder (SarafemÒ , fluoxetine hydrochloride). It is designated (±)-N-methyl-3-phenyl-3-propylamine hydrochloride and has the empirical formula of C17H18F3NO  -HCl. Its molecular weight is 345.79. The structural formula is:

Prozac Drug
Fluoxetine hydrochloride is a white to off-white crystalline solid with a solubility of 14 mg/mL in water.

Each PulvuleÒ contains fluoxetine hydrochloride equivalent to 10 mg (32.3 mmol), 20 mg (64.7 mmol), or 40 mg (129.3 mmol) of fluoxetine. The Pulvules also contain starch, gelatin, silicone, titanium dioxide, iron oxide, and other inactive ingredients. The 10- and 20-mg Pulvules also contain FD&C Blue No. 1, and the 40-mg Pulvule also contains FD&C Blue No. 1 and FD&C Yellow No. 6.

Each tablet contains fluoxetine hydrochloride equivalent to 10 mg (32.3 mmol) of fluoxetine. The tablets also contain microcrystalline cellulose, magnesium stearate, crospovidone, hypromellose, titanium dioxide, polyethylene glycol, and yellow iron oxide. In addition to the above ingredients, the 10-mg tablet contains FD&C Blue No. 1 aluminum lake and polysorbate 80.

The oral solution contains fluoxetine hydrochloride equivalent to 20 mg/5 mL (64.7 mmol) of fluoxetine. It also contains alcohol 0.23%, benzoic acid, flavoring agent, glycerin, purified water, and sucrose.

Prozac WeeklyÔ capsules, a delayed-release formulation, contain enteric-coated pellets of fluoxetine hydrochloride equivalent to 90 mg (291 mmol) of fluoxetine. The capsules also contain D&C Yellow No. 10, FD&C Blue No. 2, gelatin, hypromellose, hydroxypropyl methylcellulose acetate succinate, sodium lauryl sulfate, sucrose, sugar spheres, talc, titanium dioxide, triethyl citrate, and other inactive ingredients

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