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Why is this medication prescribed?Return to top
Glipizide is used to treat type 2 (noninsulin-dependent) diabetes (formerly 'adult-onset'), particularly in people whose diabetes cannot be controlled by diet alone. Glipizide lowers blood sugar by stimulating the pancreas to secrete insulin and helping the body use insulin efficiently. The pancreas must be capable of producing insulin for this medication to work. Glipizide is not used to treat type 1 (insulin-dependent) diabetes (formerly 'juvenile-onset').

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
Glipizide Drug

How should this medicine be used?Return to top
Glipizide comes in tablets to take by mouth. It is usually taken once a day, 30 minutes before breakfast. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take glipizide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Continue to take glipizide even if you feel well. Do not stop taking glipizide without talking to your doctor.

What special precautions should I follow?Return to top
Before taking glipizide,

tell your doctor and pharmacist if you are allergic to glipizide or any other drugs.
tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially antibiotics, anticoagulants ('blood thinners') such as warfarin (Coumadin), dexamethasone (Decadron), diuretics ('water pills'), estrogens, isoniazid (INH), MAO inhibitors , medications for high blood pressure or heart disease, niacin, oral contraceptives, phenytoin (Dilantin), prednisone, probenecid (Benemid), and vitamins.
tell your doctor if you have or have ever had kidney, liver, heart, or thyroid disease or a severe infection.
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking glipizide, call your doctor.
if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking glipizide.
plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Glipizide may make your skin sensitive to sunlight.
What special dietary instructions should I follow?Return to top
Be sure to follow all exercise and dietary recommendations made by your doctor or dietitian. It is important to eat a healthy diet.

Alcohol may cause a decrease in blood sugar. Ask your doctor about the safe use of alcoholic beverages while you are taking glipizide.

What should I do if I forget a dose?Return to top
Before you start taking glipizide, ask your doctor what to do if you forget to take a dose. Write these directions down so you can refer to them later.

As a general rule, take the missed dose as soon as you remember it unless it is almost time for the next dose. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?Return to top
You should know the symptoms of low and high blood sugar and what to do if you have them.

Eat or drink a food or beverage with sugar in it, such as hard candy or fruit juice, and call your doctor immediately if you have any of the symptoms of hypoglycemia (low blood sugar) :

dizziness or lightheadedness
nervousness or irritability
sudden changes in behavior or mood
numbness or tingling around the mouth
pale skin
sudden hunger
clumsy or jerky movements
Call your doctor immediately if you have any of the following symptoms of hyperglycemia (high blood sugar):

extreme thirst
frequent urination
extreme hunger
blurred vision
If high blood sugar is not treated, a serious, life-threatening condition called diabetic ketoacidosis could develop. Call your doctor immediately if you have any of the these symptoms:

dry mouth
upset stomach and vomiting
shortness of breath
breath that smells fruity
decreased consciousness
Glipizide may cause side effects. If you experience any of the following symptoms, call your doctor immediately:

skin rash
itching or redness
exaggerated sunburn
yellowing of the skin or eyes
light-colored stools
dark urine
unusual bleeding or bruising
sore throat
What storage conditions are needed for this medicine?Return to top
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdoseReturn to top
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

What other information should I know?Return to top
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to glipizide.

To monitor the effectiveness of glipizide, measure the amount of sugar (glucose) in your blood or urine (when blood sugar is above a certain high level, you will have sugar in your urine). For these measurements, you will need special paper tapes, tablets, or plastic strips that change color depending on how much sugar is present. You also can use a blood glucose meter to measure the amount of sugar in your blood. Your doctor also may ask you to test your urine for ketones (substances present when diabetes is not under control). Follow your doctor's directions for testing your urine and blood and for recording the results. If your blood sugar is high or if sugar or ketones are present in your urine, call your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

Brand namesReturn to top

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