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Losartan is a drug used to treat high blood pressure (hypertension) and has been examined for congestive heart failure and diabetic nephropathy. It is marketed as Cozaar by Merck Sharp and Dohme and as Hyzaar in combination with the thiazide diuretic hydrochlorothiazide (HCT).

Losartan was the first member of the recently introduced class of angiotensin II receptor antagonists. It blocks the action of the peptide hormone angiotensin on its receptors, decreasing arterial vascular tone and production of aldosterone.

Cozaar Drug
Essential hypertension
Hypertension with left ventricular hypertrophy for lowering the risk of cardiovascular morbidity and mortality
Diabetes mellitus type 2 with proteinuria for slowing down the progression of kidney disease
Because of proven effectivity and lower costs, the first choice of drug for essential hypertension is a thiazide or beta blocker. The primary use of losartan is for proven stroke prevention. A clinical trial called LIFE demonstrated that losartan works significantly better than atenolol in preventing stroke

Adverse effects
Adverse effects of Losartan include:


Other useful drug information: Metronidazole | Nystatin | Phenobarbital | Carisoprodol | Atorvastatin | Lasix | Glipizide

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