Please select first letter of the drug, then select name
from the list in the second window and click Go!
First letter: list of names:

Avandia



Rosiglitazone is an anti-diabetic drug from the thiazolidinedione class. It is being marketed as Avandia® by the pharmaceutical company GlaxoSmithKline, both as a standalone preparation and in combination with metformin (Avandamet®). Another combination drug approved by the FDA is Avandaryl® (with glimepiride).


Avandia Drug
Like other thiazolidinediones, its mechanism of action is by activation of the intracellular receptor class of the peroxisome proliferator-activated receptors (PPARs), specifically PPARγ. Rosiglitazone is a pure ligand of PPARγ, and has no PPARα-binding action. Apart from its effect on insulin resistance, it appears to have an anti-inflammatory effect: nuclear factor kappa-B (NFκB) levels fall and inhibitor (IκB) levels increase in patients on rosiglitazone (Mohanty et al).

Mohanty P, Aljada A, Ghanim H, Hofmeyer D, Tripathy D, Syed T, al-Haddad W, Dhindsa S, Dandona P. Evidence for a potent antiinflammatory effect of rosiglitazone. J Clin Endocrinol Metab 2004; 89:2728-35.

Other useful drug information: Coumadin | Lasix | Baclofen | Viagra | Fosamax | Augmentin | Avelox

Page Content: avandia , avandia side effects , avandia drug , avandia com , avandia 8 mg , avandia generic , side effects of avandia , avandia 4 mg , avandia weight gain , what is avandia , actos avandia .

This site is only for information purposes, specific treating and dosage also any information here should not be used
to diagnose or treat health problems.
Regulatory or medical requirements may wary in different countries, this information is intended for U.S. citizens.

DietList.net Copyright © 2006-2012. All Rights Reserved.