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Albumin




Albumin (Latin: albus, white) refers generally to any protein with water solubility, which is moderately soluble in concentrated salt solutions, and experiences heat coagulation (protein denaturation). Substances containing albumin, such as egg white, are called albuminoids. The term also refers to a specific blood plasma protein that is produced in the liver and forms a large proportion of all plasma protein. Albumin normally constitutes about 60% of human plasma protein; all other proteins present in blood plasma are referred to collectively as globulins. Human serum albumin is the human version.


Albumin is essential for maintaining the oncotic pressure needed for proper distribution of body fluids between intravascular compartments and body tissues. Albumin is negatively charged. The glomerular basement membrane is also negatively charged; this prevents the filtration of albumin in the urine. In nephrotic syndrome, this property is lost, and there is more albumin loss in the urine. Nephrotic syndrome patients are given albumin to replace the lost albumin.
Albumin Drug

Because smaller animals (for example rats) function at a lower blood pressure, they need less oncotic pressure to balance this, and thus need less albumin to maintain proper fluid distribution.

Functions of albumin
Maintains osmotic pressure
Transports thyroid hormones
Transports other hormones, particularly fat soluble ones
Transports fatty acids ("free" fatty acids)
Transports unconjugated bilirubin
Transports many drugs
Competitively binds calcium ions (Ca2+)
Buffers pH


Causes of albumin deficiency (hypoalbuminemia)
Cirrhosis of the liver (most commonly)
Decreased production (as in starvation)
Excess excretion by the kidneys (as in nephrotic syndrome)
Excess loss in bowel (protein losing enteropathy)
Mutation causing analbuminemia (very rare)
Acute disease states (referred to as a negative acute phase reactant)

Testing for albumin loss via the kidneys
Albumin may be lost via the kidneys in a number of diseases, including kidney disease and diabetes. This can be detected by a urine test . Depending on the amount of albumin lost, a patient may have normal renal function, microalbuminuria, or albuminuria.

Other useful drug information: Lortab | Lamisil | Luvox | Mucinex | Topamax | Claritin | Elidel

Page Content: albumin globulin ratio , albumin level , albumin bovine serum , albumin serum , albumin low .

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to diagnose or treat health problems.
Regulatory or medical requirements may wary in different countries, this information is intended for U.S. citizens.

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